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1)  targeting [英]['tɑ:ɡɪt]  [美]['tɑrgɪt]
靶向性
1.
Progress in targeting MRI contrast agents;
靶向性磁共振成像造影剂的研究进展
2.
Whether the hepatitis B virus envelope as a gene transfer vector has targeting ability for liver cancer;
乙肝病毒衣壳作为肝癌基因转移载体对肝癌是否有靶向性
3.
Research on targeting of O-Carboxymethylated Chitosan-PLA Adriamycin nanoparticles in rats;
O-羧甲基乳糖酰化壳聚糖-聚乳酸阿霉素纳米粒在大鼠体内的靶向性研究
2)  Target [英]['tɑ:ɡɪt]  [美]['tɑrgɪt]
靶向性
1.
Experimental Study of pcDNA3/AFP/TK/Angio Fusion Gene Targeting Therapy for Human Primary Liver Cancer;
pcDNA3/AFP/TK/Angio融合基因靶向性治疗人原发性肝癌的实验研究
2.
Observation of AFP/ANGIO/TK Targeted Fusion Gene Therapy of Human Primary Hepatocellular Carcinoma;
AFP/ANGIO/TK靶向性融合基因治疗人原发性肝癌的效果观察
3.
The development of targeted gene therapy in gliomas;
胶质瘤的靶向性基因治疗进展
3)  Targeted [英]['tɑ:ɡɪt]  [美]['tɑrgɪt]
靶向性
1.
Mechanism of Self-made Surfactant Fluorocarbon-filled Microbubbles (SFCMB) Conjugated with Phosphatidylserine (PS) Targeted to Activated Leukocytes;
自制“表活显”对白细胞的靶向性机制研究
2.
Strategies of tumor-targeted gene therapy;
肿瘤基因治疗的靶向性策略
3.
Preparation of Targeted Paclitaxel Liposomes and Study of Their Drug Effect;
靶向性紫杉醇脂质体的制备及药效的初步研究
4)  targeting ability
靶向性
1.
Preparation of cardiomyocyte-targeting liposomes and their targeting ability in vitro;
心肌细胞靶向脂质体的制备及体外靶向性研究
2.
Fusion expression and targeting ability of the single-chain Fv antibody against the anti-fecundity immunity molecule,soluble immature egg antigen SIEA26-28kDa from Schistosoma japonica;
抗日本血吸虫生殖功能分子SIEA26~28kDa单链抗体与EGFP的融合表达及靶向性研究
3.
Polymeric micelles possess several advantages as compared with other drug carriers,such as high loading capacity,small particle size,long-circulation time,targeting ability and so on.
聚合物胶束作为药物载体具有许多优势,如载药能力强、粒径小、体内循环时间长、具有主动和被动靶向性等特点。
5)  targeting characteristics
靶向特性
1.
To review the research of block copolymer micelles as delivery system for poorly soluble(antineoplastic) carrier over the last 10 years,including the composition,preparation methods and factors which influence the loading efficiency,physicochemical properties,and targeting characteristics of block copolymer micelles.
根据国外有关文献,综述了10年来嵌段共聚物胶束作为难溶性抗肿瘤药物载体的研究进展,包括嵌段共聚物胶束组成、制备方法及影响因素、理化性质和靶向特性的研究。
6)  Liver targeting
肝靶向性
1.
Effect of diameter of adriamycin polybutylcyanoacrylate nanoparticles on liver targeting;
阿霉素聚氰基丙烯酸正丁酯纳米粒粒径对肝靶向性的影响
2.
Preparation and liver targeting of floxuridinyl dibutyrate solid lipid nanoparticles;
氟尿苷二丁酸酯固体脂质纳米粒的制备和肝靶向性研究
补充资料:靶向给药
分子式:
CAS号:

性质:靶制剂选择性地与靶细胞结合产生药理效应的过程。由于不同的给药途径药靶物制剂可以进入不同的位置,而产后不同的靶向性和作用特点。如脂质体制剂,可以静脉、腹腔、肌肉、皮下或淋巴结注射,也可以支气管给药或大脑内、脊椎给药。静脉给药时,脂质体在体内优先被富含网状内皮细胞的组织(肝脾)所摄取,并迅速被单核吞噬细胞吞噬和降解。主要包括脂质体给药系统、受体靶向及磁性药物。脂质体制剂是把药物包裹在双分子脂质膜中,此种磷脂膜与生物膜类似,成为药物的载体,它与细胞膜亲和力强,使癌细胞摄取增多,提高疗效,增加耐受性。受体靶向是利用脂质体的表面有共价键与抗肿瘤细胞表面抗原的单克隆抗体结合,使脂质体在肿瘤细胞内大量集中,提高抗肿瘤细胞的选择性。磁性药物是指药物与高磁性的硫酸铁结合,在给药后,体外使用强大的磁场,使肿瘤部位处于此种强大磁场之下,药物被选择性地集中在肿瘤细胞,提高治疗指数。 

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