1) Asymmetric dihydroxylation
不对称二羟基化
1.
METHODS The asymmetric dihydroxylations of trans stilbene, naphthyl allyl ether and styrene were catalyzed by DHQD PHAL OPEG OMe/OsO 4 with tBuOH H 2O (1∶1) as the solvent and K 3Fe(CN) 6 as the cooxidant.
方法 以 t Bu OH/H2 O(1∶1)为溶剂 ,以 K3Fe(CN ) 6 为共氧化剂 ,用 DHQD- PHAL -OPEG- OMe/Os O4 分别催化反式二苯乙烯、萘基烯丙基醚和苯乙烯的不对称二羟基化反应 。
2.
The asymmetric dihydroxylation of ortho-substituted 1,2-diphenylethenes affords the corresponding diols in good yields (77～89%) and high enantiomeric excesses (73～98%) in the presence of catalytic amount OsO4 and four different chiral ligands respectively.
邻位取代１，２－二苯乙烯催化不对称二羟基化反应张生勇，孙晓莉（第四军医大学化学教研室西安７１００３２）关键词 不对称二羟基化，手性二醇近年催化的反式稀烃的不对称二羟基化反应取得明显进展［１］，但催化的邻位取代的１，２－二苯乙烯类化合物。
2) asymmetric dihydroxylation
不对称二羟化
1.
Synthesis and utilization of two novel chirl liands for asymmetric dihydroxylation;
两种不对称二羟化反应的新型手性配体的合成及其应用
2.
A novel recoverable and reusable chiral ligand for asymmetric dihydroxylation of olefins was prepared from 1,4-difluoroanthraquinone by two steps.
在不对称二羟化反应的 2种不同体系中 ,该配体对 6种烯烃的反应表现出很高的对映选择性 (80 %～97% )和催化活性 (80 %～ 94 % ) 。
3.
Ethyl trans-p-methoxycinnamate was transformed into ethyl (2R,3S)-2,3-dihydroxy-3-(4-methoxyphenyl)propionate(2) in 87% yield and 99%ee by osmium-catalyzed asymmetric dihydroxylation with 1,4-bis(9-O-quininyl)phthalazine as the chiral ligand.
以1,4-双(9-O-奎宁基)-2,3-二氮杂萘为手性配体,经锇催化的不对称二羟化反应将反式-对甲氧基肉桂酸乙酯转化为(2R,3S)-2,3-二羟基-3-(4-甲氧基苯基)丙酸乙酯(2),收率87%,ee值大于99%;2与氯化亚砜反应得到地尔硫的手性中间体(4S,5R)-4-(4-甲氧基苯基)-5-乙氧羰基-1,3-二氧杂-2-氧代硫杂环戊烷,收率85%。
4) asymmetric amino-hydroxylation
不对称氨羟基化
1.
The osmium-catalyzed asymmetric dihydroxylation (AD) and asymmetric amino-hydroxylation (AA) of olefins provide the most effective methods for the preparation of chiral vicinal diols and B-amino diols respectively.
锇催化的烯烃不对称二羟基化(AD)和不对称氨羟基化(AA)反应是制备手性邻二醇和β-氨基醇的有效方法，在有机合成及药物合成中有着重要作用。
5) asymmetric hydroxylation
不对称羟基化
6) asymmetric hydroxyl
不对称羟基
1.
Selective protection of the asymmetric hydroxyl of 5-bromo-2-hydroxyphenylmethanol was investigated by method of fractional steps.
采用分步法对5-溴-2-羟基苯甲醇中的不对称羟基进行了选择性保护。
补充资料：不对称羟基化
分子式：
CAS号：
性质：应用羟基化反应进行不对称合成。
CAS号：
性质：应用羟基化反应进行不对称合成。
说明：补充资料仅用于学习参考，请勿用于其它任何用途。
参考词条