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1)  nateglinide cis-isomer
那格列奈顺式异构体
1.
4-Isopropylbenzoic acid was hydrogenated to give a mixture of cis-and trans-4-isopropyl-cyclohexanecarboxylic acid (76∶24),the mixture was transformed into the acylchoride with PCl5 ,and then condensed with D-phenylalaine,after recrystallization from acetonitrile,nateglinide cis-isomer was obtained which may be served as the reference in the quality control of nateglinide.
4-异丙基苯甲酸经氢化还原得4-异丙基环己基甲酸的顺式和反式(76∶24)混合物,不分离制成酰氯后,与D-苯丙氨酸缩合,得那格列奈及其顺式异构体混合物,经乙腈重结晶得那格列奈顺式异构体,可作为那格列奈质量控制的参照物。
2)  cis-nateglinide
顺式那格列奈
3)  nateglinide
那格列奈
1.
Study on Stability of Nateglinide Polymorphism;
不同晶型那格列奈的稳定性研究
2.
Determination of Degree of Stripping of Nateglinide by Reversed Phase High Performance Liquid Chromatography;
反相高效液相色谱法测定那格列奈片剂的溶出度
4)  Nateglinide tablets
那格列奈片
1.
To study and evaluate the quality of Nateglinide tablets the formulation is screened.
对研制的那格列奈片进行质量评价与研究。
2.
To develop a method for dissolution determination of nateglinide tablets in vitro, the dissolution was determinedwith paddle method (50 r·min~1) in 500 mL pH6 .
建立了那格列奈片的体外溶出度测定方法,以pH6。
3.
OBJECTIVE To establish the dissolution method for nateglinide tablets.
目的 :建立那格列奈片的体外溶出度的测定方法。
5)  D-nateglinide
D-那格列奈
6)  L-nateglinide
L-那格列奈
补充资料:那格列奈
分子式:暂无
分子量:暂无
CAS号:暂无

性质:暂无

制备方法:暂无

用途:暂无

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