Clinicopathological study of uterine serous carcinoma and endometrial intraepithelial carcinoma;

Expression and significance of PTEN and p53 in uterine serous carcinoma and endometrioid carcinoma;

Clinico-pathologic features and treatment of uterine papillary serous carcinoma;

ER, PR, nm23-Hl, E-cadherin, AKT and pAKT expressions were measured by using of immunohistochemical staining in ovarian clear cell adenocarcinoma, ovarian serous adenocarcinoma, ovarian borderline and benign serous cystadenoma paraffin-embedded specimen.

Objective:To investigate the expression and significance of WT-1, P53, matrix metalloproteinase-9 (MMP-9) and tissue inhibitor of metalloproteinase-2 (TIMP-2) in ovarian papillary serous carcinomas, and approach the relationship between the expression of these immuno- marker in ovarian papillary serous carcinomas and the degree of its differentiation or the metastasis.

Methods 28 patients with ovarian clear cell carcinoma and 43 patients with ovarian serous cystadenocarcinoma were compared in clinical symptoms,tumor size,ascites and endometriosis.

Analysis in the number of CD4~+CD25~+ and CD8~+ T lymphocytes in ovarian serous carcinoma;

Recently, following the further understanding of clinical pathomorphology characteristic about ovarian serous carcinoma and the development of molecular genetics, we have a new recognition about the pathogenesis and pathomorphology characteristic of ovarian serous carcinoma, and propose a dualistic theory model for ovarian serous carcinogenesis.