Application of tandem reactions in the design of organic chemistry experiment

The examples of catalytic promiscuity in Michael addition, Markovnikov addition, al-dol condensation, oxidation reactions and tandem reactions are reviewed.

Without the separation of intermediates, tandem reactions could afford products with higher yield than traditional reactions.

In this thesis, we have studied a series of new types of imine involved cascade reactions and liquid phase syntheses.

Cascade reaction is one of the important reaction in organic chemistry , it enable a rapid increase in molecular complexity from readily available starting compounds and construct several covalent bonds in one-pot, it is an efficient synthesis strategy of constructing complicated organic compounds economically and conveniently.