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1)  APP/PS1 transgenic
APP/PS1转基因
2)  APP/PS1 transgenic mouse
APP/PS1转基因小鼠
1.
Distribution of zinc ions and zinc transporter-6 in the APP/PS1 transgenic mouse cerebellum
锌离子与锌转运体6在APP/PS1转基因小鼠小脑内的分布
2.
Objective To investigate the expression change and distribution of zinc transporter-3(ZnT-3)in the hippocampus and cortex of APP/PS1 transgenic mouse.
目的研究锌转运蛋白3(ZnT-3)在APP/PS1转基因小鼠大脑皮质及海马内的分布和表达变化。
3.
Results ZnT3 was predominately distributed in the senile plaques of the APP/PS1 transgenic mouse brain,and it was also seen .
目的研究锌转运体-3(zinc transporter3,ZnT3)在APP/PS1转基因小鼠大脑皮层及海马内的表达,探讨ZnT3与β-淀粉样蛋白(β-amyloid,Aβ)在老年斑内的定位分布及相关性。
3)  APP/PS1 transgenic mouse
APP/PS1转基因鼠
1.
Objective To investigate the distribution of free zinc ions and β-amyloid precursor protein (APP) in the senile plaques of an Alzheimer s diseased animal model,the APP/PS1 transgenic mouse.
目的研究阿尔茨海默病(AD)动物模型-APP/PS1转基因鼠大脑内游离锌离子和β淀粉样蛋白前体蛋白(APP)在老年斑内的分布。
4)  APP/PS1 transgenic mice
APP/PS1双转基因小鼠
5)  App transgene
App转基因
6)  PS1 gene
PS1基因
1.
The absolute expression levels of APP and PS1 genes were quantified in 45 AD patients,25 patients with vascular dementia(VD) and 60 healthy controls by real-time quantitative PCR using SYBR Green I.
为了检测Alzheimer病(Alzheimer’s disease,AD)患者外周血中淀粉样前体蛋白(Amyloid Precursor Protein,APP)基因及早老素1(Presenilin 1,PS1)基因的表达情况,进而探讨APP及PS1基因的表达与AD的相关性,采用SYBRGreenⅠ的方法对45例AD患者、25例血管性痴呆(vascular dementia,VD)患者及60名正常对照组样本的mRNA进行绝对定量,检测得到APP基因及PS1基因在对照组中的表达水平分别为0。
补充资料:APP
   无规聚丙烯是生产等规聚丙烯的副产物,平均分子量3000-10000。有时可高达几万。室温下为天定形微带粘性的白色蜡状固体,相对密度0.86,软化点90-150 ℃,闪点220-230 ℃.燃点300-330 ℃,玻璃化温度>-25℃,脆化温度-6~-15℃,拉伸强度  <0.784 MPa, 200 ℃开始分解。溶于烷烃、芳烃和酯类等有机溶剂,不溶乙醇、丙酮和水。由于分子量小,结构不规整、内聚力低,故机械性能和耐热性较差。
    用于制取热熔胶、压敏胶、铺路胶粘剂等。储存于阴凉、通风的库房内,防火、防热。
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