1) O-methylsinomenine

O-甲基青藤碱二醛
1.
Sinomenine (1) was O-methylated under Mitsunobu conditions to give O-methylsinomenine (2), which was converted into O-methylsinomeninedialdehyde (5) through a procedure of acid hydrolysis, boro-hydride reduction and thereafter oxidation with NaIO4.
对青藤碱进行Mitsunobu甲基化反应,得到O-甲基青藤碱(2);2经过酸性水解、硼氢化还原以及高碘酸钠氧化开环得到O-甲基青藤碱二醛(5);在哌啶存在下对5进行羟醛缩合反应,区域选择性地闭环生成具有(+)-C-normorphinan骨架的化合物(8S,12S,13R)-6,7-didehydro-3,4-dimethoxy-16-methyl-C-normorphinan-7-carboxaldehyde(7);经过以上五步反应,7的总收率约35%。
2) benzoyl sinomenine

苯甲酰青藤碱
1.
Anti-inflammatory and analgesic effects of benzoyl sinomenine;

苯甲酰青藤碱的镇痛抗炎作用
3) 11α,12β-di-O-2-methylbutyryl-tenacigenin B

11α,12β-二-O-2-甲基丁酰基-通光藤苷元B
1.
Their structures were identified as 11α,12β-di-O-2-methylbutyryl-tenacigenin B (Ⅰ),11α-O-2-methylbutyryl-12β-O-acetyl-tenacigenin B (Ⅱ),tenacissoside H (Ⅲ),and marsdenoside A (Ⅳ),respectively.
结果从通光藤的70%乙醇提取物中分离得到了4个C21甾体化合物,分别鉴定为11α,12β-二-O-2-甲基丁酰基-通光藤苷元B(Ⅰ)、11α-O-2-甲基丁酰基-12β-O-乙酰基-通光藤苷元B(Ⅱ)、通光藤苷H(Ⅲ)和marsdenosideA(Ⅳ)。
4) elegreen

甲基柑青醛
5) sinomenine
[,sainəu'meni:n]

青藤碱
1.
Preparation of sinomenine gel and its skin penetration test in vitro;

青藤碱凝胶剂的制备及体外渗透性能研究
2.
Determination of Sinomenine in Sinomenium acutum and Sinomenium Tablets by Capillary Electrophoresis with High Frequency Conductivity Detector;
毛细管电泳高频电导法测定青风藤药材及制剂中青藤碱的含量
3.
Quantitaive Determination of Sinomenine in “Zheng Qing Feng Tong Ning Tabellae”;

高效薄层双波长扫描法测定正青风痛宁片中青藤碱的含量
6) SIN
[英][sɪn] [美][sɪn]

青藤碱
1.
Suppressive effects of SIN on immunological function and cytokine production by T cells from the patients with SLE;
青藤碱对红斑狼疮患者外周血T细胞的抑制作用及机制探讨
2.
Objective To explore the molecular mechanism of immunosuppressive efficacy of alkaloid Sinomenine (SIN) against acute rejection following renal transplantation in rats.
目的探讨青藤碱(SIN)对大鼠肾移植术后急性排斥反应免疫抑制作用的分子机制。
3.
Objectives To evaluate the effects of the alkaloid sinomenine (SIN) on T cell proliferation and acute rejection in rat renal allografts.
目的 探讨青藤碱 (SIN)对大鼠肾移植急性排斥反应 (AR)抑制作用的机制。
补充资料:[3-(aminosulfonyl)-4-chloro-N-(2.3-dihydro-2-methyl-1H-indol-1-yl)benzamide]
分子式:C16H16ClN3O3S
分子量:365.5
CAS号:26807-65-8
性质:暂无
制备方法:暂无
用途:用于轻、中度原发性高血压。
分子量:365.5
CAS号:26807-65-8
性质:暂无
制备方法:暂无
用途:用于轻、中度原发性高血压。
说明:补充资料仅用于学习参考,请勿用于其它任何用途。
参考词条