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1)  CTPZ
川芎嗪甲酸
1.
Effect of CTPZ on Cytosolic Free Calcium Concentration in Smooth Muscle Cells
川芎嗪甲酸对平滑肌细胞游离钙浓度的影响
2)  Tetramethylpyrazine phosphate
磷酸川芎嗪
1.
Preparation of tetramethylpyrazine phosphate pulsed-release tablets;
磷酸川芎嗪脉冲释放片的研制
2.
Preparation of tetramethylpyrazine phosphate sustained-release tablets;
磷酸川芎嗪缓释片的研制
3.
Effect of cyclodextrins on the intranasal absorption of tetramethylpyrazine phosphate;
环糊精及其衍生物对磷酸川芎嗪鼻黏膜吸收的促进作用
3)  ligustrazine hydrochloride
盐酸川芎嗪
1.
Study on preparation of ligustrazine hydrochloride liposome;
盐酸川芎嗪脂质体喷雾剂的研制
2.
Preparation of oral timed release pellets of ligustrazine hydrochloride;
盐酸川芎嗪口服定时释药微丸的制备
3.
Uniform design method for optimizing proportion of transdermal penetration enhancers of ligustrazine hydrochloride;
均匀设计法筛选盐酸川芎嗪促透剂组方的最佳配比
4)  Tetramethylpyrazine phosphate(TMPP)
磷酸川芎嗪
1.
Objective To investigate the absorption characteristic of tetramethylpyrazine phosphate(TMPP) in various intestinal segments.
目的研究磷酸川芎嗪的大鼠在体肠吸收性质。
5)  Ligustrazine phosphate
磷酸川芎嗪
1.
Study on Bioequivalence of Ligustrazine Phosphate Capsules in Healthy Volunteers;
磷酸川芎嗪胶囊的人体生物等效性研究
2.
Determination of Ligustrazine Phosphate for Injection by HPLC;
HPLC法测定注射用磷酸川芎嗪中主药的含量
3.
Preparation and in- vitro drug release of Ligustrazine Phosphate Sustained- release Patches;
磷酸川芎嗪缓释透皮贴剂的制备及体外释放度测定
6)  tetramethylpyrazine hydrochloride
盐酸川芎嗪
1.
[Objective] To study the effects of Borneol-Menthol binary eutectic mixture on transdermal permeation of tetramethylpyrazine hydrochloride(TMPH)and to investigate the feasibility of traditional chinese medicine(i.
[目的]研究冰片-薄荷脑二元低共熔混合物对盐酸川芎嗪透皮经皮渗透的影响,考察其作为药物经皮渗透促进剂的可行性。
2.
hy926 as a model to analyze the activity changes of relative enzymes and regulation mechanism of relative signal pathways of the model under the condition of injury by angiotensin II (AngII) and / or protection by tetramethylpyrazine hydrochloride (TMP·HCl), an effective component of traditional Chinese medicine Ligusticum chuanxiong Hort.
hy926为研究模型,从细胞水平上分析了血管紧张素Ⅱ(angiotensinⅡ,AngⅡ)损伤过程及中药川芎的一种有效成分——盐酸川芎嗪(tetramethylpyrazine hydrochloride,TMP·HCl)保护过程中内皮细胞的相关酶活性变化及信号转导规律。
3.
Aim To determine the concentration and dynamic chan ge s of tetramethylpyrazine hydrochloride in the retinal tissue following intraperi toneal injection in rabbits.
目的 测定腹腔注射盐酸川芎嗪后不同时间兔眼视网膜川芎嗪的浓度 ,计算其药动学参数 ,研究其药动学特点。
补充资料:川芎嗪
分子式:C8H12N2
分子量:136.20
CAS号:1124-11-4

性质:该品带结晶水时熔点74-77℃,无水物熔点86℃;沸点190℃。其盐酸盐二水合物为白色结晶,熔点91℃,易溶于水,溶于乙醇及氯仿,极微溶于苯。无水物熔点156℃。

制备方法:由丁酮与亚硝酸乙酯缩合生成丁二酮单肟,再经还原、环合而得甲甲基吡嗪。环合反应产物进行水蒸气蒸馏,馏出物冷却、结晶、过滤,得四甲基吡嗪粗品。精制时采用水重结晶和活性炭脱色。制备其盐酸盐时,可将其在丙酮中滴加含15%-20%氯化氢的乙醇溶液成盐。

用途:用于药物生产。

说明:补充资料仅用于学习参考,请勿用于其它任何用途。
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