Relationship of the chromosomel gyrA gene mutation and ciprofloxacin resistance of Acinetobacter baumannii isolated from the sputum of patients with craniocerebral injury;

Studies on relationship between gyrA gene mutation and quinolone resistance of Pseudomonas aeruginosa;

gyrA gene mutations in quinolone-resistant Shigellae flexneri;

Shigella GyrA Mutations and their Relations with Quinolones Resistance;

Objective:To isolate and assess levofloxacin resistance of Helicobacter pylori;Examine the difference of gyrA between the resistance-strains and susceptive-strains by sequencing, and probe the role of the mutation of gyrA gene in the development of resistance;and construct the gene chip for detecting the mutations of gyrA.

Detection of resistence to erythromycin and related resistant genes in streptococcus pneumoniae strains;

Analysis of enterococcal antimicrobial resistance and detection on antibiotics-resistant genes in children

Resistant genes encoding β-lactamases,aminoglycoside modifying enzymes and antiseptic resistance were detected by PCR amplification and verified by DNA sequencer.

Analysis of drug resistance genes in extended spectrum β-lactamases producing Escherichia coli;

Disinfectant-sulfadiazine Resistance genes in Escherichia coli Isolated from Elderly Wards

Objective: To understand the resistance gene spectrum and genetics characteristics of Klebsiella pneumoniae(Kpn) producting ESBLs.