Osteoclasst inhibitory lectin (OCIL), expressed by the osteoblast lineage and stomal cells, is a 270 amino acid type-Ⅱ transmembrane protein with a 113-amino acid C-type lectin motif in the extracellular domain.

Preparation and identification of monoclonal antibodies against snake venom C-type lectin like protein Agkisacutacin;

To better understand the accelerated evolution of snake venom C-type lectin-like proteins (CTL-like proteins) and to investigate the structure-function relationships, PCR was conducted to amplify cDNAs coding for the β chains of snake venom CTL-like proteins and the genomic DNA of agkisasin β.

C type lectin superfamily in snake comprises a group of proteins which display anticoagulation or various other functions.

The mannose receptor(MR) is one of the C-type lectin family which can recognize and bind the specific carbohydrates by its extracellular region.

Macrophage mannose receptor (MMR) is a member of the mammalian C-type lectin superfamily, expressing mainly on the surface of macrophage and immature dendritic cells.

The deduced amino acid sequence showed high similarity to C-type lectin from Fundulus heteroclitus.

C-type lectins are key players in the immune system, mediating clearance of pathogens and cell-cell interactions in the innate and adaptive immunity.

C-type lectins,as a kind of pattern recognition receptors in innate immune,can specificly recognize sugars in the surface of pathogen microorganisms in the presence of Ca~(2+),and cause a series of immune response to resist pathogens invasion effectively.